TAS2R41

TAS2R41
Identifiers
Aliases	TAS2R41 , T2R41, T2R59, taste 2 receptor member 41
External IDs	OMIM: 613965 MGI: 2681273 HomoloGene: 16412 GeneCards: TAS2R41
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q35 Start 143,477,873 bp [1] End 143,478,796 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 B2.1 Start 42,411,469 bp [2] End 42,412,398 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prosencephalon lung brain aorta organ system blood material anatomical entity multicellular organism popliteal artery Top expressed in embryo More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 259287 387353 Ensembl ENSG00000221855 ENSG00000284982 ENSMUSG00000048284 UniProt P59536 P59532 RefSeq (mRNA) NM_176883 NM_207028 RefSeq (protein) NP_795364 NP_996911 Location (UCSC) Chr 7: 143.48 – 143.48 Mb Chr 6: 42.41 – 42.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor type 2 member 41 is a protein that in humans is encoded by the TAS2R41 gene. ^{[5] [6]}

See also

• Taste receptor

References

1. ENSG00000284982 GRCh38: Ensembl release 89: ENSG00000221855, ENSG00000284982 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048284 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID   12379855. S2CID   20426192.
6. "Entrez Gene: TAS2R41 taste receptor, type 2, member 41".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi: 10.1074/jbc.R100054200 . PMID   11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID   12139982. S2CID   37807140.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi: 10.1016/S0092-8674(03)00071-0 . PMID   12581520. S2CID   718601.
• Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID   12584440. S2CID   1542970.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi: 10.1093/molbev/msi027 . PMID   15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC   1449719 . PMID   15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.