GPR88

Last updated
GPR88
Identifiers
Aliases GPR88 , STRG, COCPMR, G protein-coupled receptor 88
External IDs OMIM: 607468; MGI: 1927653; HomoloGene: 11104; GeneCards: GPR88; OMA:GPR88 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022049

NM_022427

RefSeq (protein)

NP_071332

NP_071872

Location (UCSC) Chr 1: 100.54 – 100.54 Mb Chr 3: 116.04 – 116.05 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 88 is a protein that in humans is encoded by the GPR88 gene. [5] [6] [7] [8] [9]

Ligands

Agonists

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181656 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000068696 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
  6. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
  7. Mizushima K, Miyamoto Y, Tsukahara F, et al. (2001). "A novel G-protein-coupled receptor gene expressed in striatum". Genomics. 69 (3): 314–21. doi:10.1006/geno.2000.6340. PMID   11056049.
  8. Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
  9. Van Waes V, Tseng K, Steiner H (2011). "GPR88 - a putative signaling molecule predominantly expressed in the striatum: Cellular localization and developmental regulation". Basal Ganglia. 1 (2): 83–89. doi:10.1016/j.baga.2011.04.001. PMC   3144573 . PMID   21804954.
  10. Rahman MT, Decker AM, Ben Hamida S, Perrey DA, Chaminda Lakmal HH, Maitra R, Darcq E, Kieffer BL, Jin C. Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation. J Med Chem. 2023 Feb 23;66(4):2964-2978. doi : 10.1021/acs.jmedchem.2c01983 PMID   36749855