GPR83

GPR83
Identifiers
Aliases	GPR83 , GIR, GPR72, G protein-coupled receptor 83
External IDs	OMIM: 605569; MGI: 95712; HomoloGene: 7732; GeneCards: GPR83; OMA:GPR83 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q21 Start 94,377,316 bp [1] End 94,401,419 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9 A2|9 4.4 cM Start 14,771,506 bp [2] End 14,782,085 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar vermis middle temporal gyrus cerebellar hemisphere right hemisphere of cerebellum Brodmann area 23 testicle superior frontal gyrus spinal ganglia prefrontal cortex entorhinal cortex Top expressed in olfactory tubercle nucleus accumbens pectoral muscles pectoralis minor muscle pectoralis major mammillary body lobe of prostate globus pallidus superior frontal gyrus lumbar subsegment of spinal cord More reference expression data BioGPS n/a
Gene ontology Molecular function neuropeptide Y receptor activity G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane non-motile cilium cilium Biological process response to glucocorticoid neuropeptide signaling pathway signal transduction G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10888 14608 Ensembl ENSG00000123901 ENSMUSG00000031932 UniProt Q9NYM4 P30731 RefSeq (mRNA) NM_016540 NM_001330345 NM_010287 NM_001310734 RefSeq (protein) NP_001317274 NP_057624 NP_001297663 NP_034417 Location (UCSC) Chr 11: 94.38 – 94.4 Mb Chr 9: 14.77 – 14.78 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 83 is a protein that in humans is encoded by the GPR83 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000123901 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031932 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Parker R, Liu M, Eyre HJ, Copeland NG, Gilbert DJ, Crawford J, Sutherland GR, Jenkins NA, Herzog H (Jul 2000). "Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6". Biochim Biophys Acta. 1491 (1–3): 369–75. doi:10.1016/s0167-4781(00)00023-3. PMID   10760605.
6. De Moerlooze L, Williamson J, Liners F, Perret J, Parmentier M (Nov 2000). "Cloning and chromosomal mapping of the mouse and human genes encoding the orphan glucocorticoid-induced receptor (GPR83)". Cytogenet Cell Genet. 90 (1–2): 146–50. doi:10.1159/000015650. PMID   11060465. S2CID   8439947.
7. "Entrez Gene: GPR83 G protein-coupled receptor 83".

Further reading

• Nagase T, Kikuno R, Ishikawa K, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi: 10.1093/dnares/7.2.143 . PMID   10819331.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hansen W, Loser K, Westendorf AM, et al. (2006). "G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo". J. Immunol. 177 (1): 209–15. doi: 10.4049/jimmunol.177.1.209 . PMID   16785516.