Related Research Articles
The EGF module-containing Mucin-like hormone Receptors (EMRs) are closely related subgroup of G protein-coupled receptors (GPCRs). These receptors have a unique hybrid structure in which an extracellular epidermal growth factor (EGF)-like domain is fused to a GPCR domain through a mucin-like stalk. There are four variants of EMR labeled 1-4, each encoded by a separate gene. These receptors are predominantly expressed in cells of the immune system and bind ligands such as CD55.
Prokineticin is a secreted protein that potently contracts gastrointestinal smooth muscle.
The free fatty acid receptor is a G-protein coupled receptor which binds free fatty acids. There are four variants of the receptor, each encoded by a separate gene. Preliminary findings suggest that FFAR2 and FFAR3 may interact to form a FFAR2-FFAR3 receptor heteromer.
The SREB are a group of related G-protein coupled receptors. Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors.
The Retinoic Acid-Inducible orphan G-protein-coupled receptors (RAIG) are a group of four closely related G protein-coupled receptors whose expression is induced by retinoic acid.
The neuropeptide B/W receptors are members of the G-protein coupled receptor superfamily of integral membrane proteins which bind the neuropeptides B and W. These receptors are predominantly expressed in the CNS and have a number of functions including regulation of the secretion of cortisol.
Brain-specific angiogenesis inhibitors are G-protein coupled receptors belonging to the class B secretin subfamily. Members include:
Prokineticin receptor 1, also known as PKR1, is a human protein encoded by the PROKR1 gene.
Prokineticin receptor 2 (PKR2), is a G protein-coupled receptor encoded by the PROKR2 gene in humans.
Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.
Olfactory receptor 2AP1 is a protein that in humans is encoded by the OR2AP1 gene.
Olfactory receptor 2AJ1 is a protein that in humans is encoded by the OR2AJ1 gene.
Olfactory receptor 2B11 is a protein that in humans is encoded by the OR2B11 gene.
Olfactory receptor 1N2 is a protein that in humans is encoded by the OR1N2 gene.
Olfactory receptor 2Y1 is a protein that in humans is encoded by the OR2Y1 gene.
Olfactory receptor 1S2 is a protein that in humans is encoded by the OR1S2 gene.
Olfactory receptor 2L13 is a protein that in humans is encoded by the OR2L13 gene.
Olfactory receptor 14A16 is a protein that in humans is encoded by the OR14A16 gene.
Olfactory receptor 2G6 is a protein that in humans is encoded by the OR2G6 gene.
Olfactory receptor 2J1 is a protein that in humans is encoded by the OR2J1 gene.
References
- ↑ Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi: 10.1074/jbc.M202139200 . PMID 11886876.
