GPR161

GPR161
Identifiers
Aliases	GPR161 , RE2, G protein-coupled receptor 161
External IDs	OMIM: 612250 MGI: 2685054 HomoloGene: 17824 GeneCards: GPR161
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q24.2 Start 168,079,542 bp [1] End 168,137,667 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1 H2.2|1 72.64 cM Start 165,123,358 bp [2] End 165,154,314 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence myometrium stromal cell of endometrium spinal ganglia smooth muscle tissue left uterine tube trigeminal ganglion seminal vesicula nipple Brodmann area 23 Top expressed in subiculum Region I of hippocampus proper ganglionic eminence hand morula medial ganglionic eminence hippocampus proper ascending aorta trigeminal ganglion aortic valve More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity Cellular component plasma membrane cell projection membrane ciliary membrane integral component of membrane endocytic vesicle membrane cilium recycling endosome Biological process multicellular organism development signal transduction G protein-coupled receptor signaling pathway negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning adenylate cyclase-activating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23432 240888 Ensembl ENSG00000143147 ENSMUSG00000040836 UniProt Q8N6U8 B2RPY5 RefSeq (mRNA) NM_001267609 NM_001267610 NM_001267611 NM_001267612 NM_001267613 NM_001267614 NM_007369 NM_153832 NM_001349632 NM_001349633 NM_001349634 NM_001349635 NM_001375883 NM_001375884 NM_001375885 NM_001381909 NM_001081126 NM_001310429 NM_001310430 RefSeq (protein) NP_001254538 NP_001254539 NP_001254540 NP_001254541 NP_001254542 NP_001254543 NP_722561 NP_001336561 NP_001336562 NP_001336563 NP_001336564 NP_001362812 NP_001362813 NP_001362814 NP_001368838 NP_001074595 NP_001297358 NP_001297359 Location (UCSC) Chr 1: 168.08 – 168.14 Mb Chr 1: 165.12 – 165.15 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000143147 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000040836 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Small KM, Seman CA, Castator A, Brown KM, Liggett SB (Apr 2002). "False positive non-synonymous polymorphisms of G-protein coupled receptor genes". FEBS Lett. 516 (1–3): 253–6. doi:10.1016/S0014-5793(02)02564-4. PMID   11959142. S2CID   35944696.
6. "Entrez Gene: GPR161 G protein-coupled receptor 161".

Further reading

• Schöneberg T, Schulz A, Gudermann T (2002). "The structural basis of G-protein-coupled receptor function and dysfunction in human diseases". Rev. Physiol. Biochem. Pharmacol. Reviews of Physiology, Biochemistry and Pharmacology. 144: 143–227. doi:10.1007/BFb0116587. ISBN   978-3-540-42814-5. PMID   11987825.
• Raming K, Konzelmann S, Breer H (1999). "Identification of a novel G-protein coupled receptor expressed in distinct brain regions and a defined olfactory zone". Recept. Channels. 6 (2): 141–51. PMID   9932290.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.