Taste receptor, type 2, member 31, also known as TAS2R31, is a protein which in humans is encoded by the TAS2R31 gene. [5] This bitter taste receptor has been shown to respond to saccharin in vitro. [6]
TAS2R31 is also expressed in the smooth muscle of human airways, along with several other bitter taste receptors. Their activation in these cells causes an increase in intracellular calcium ion, which in turn triggers the opening of potassium channels which hyperpolarize the membrane and cause the smooth muscle to relax. Hence, activation of these receptors leads to bronchodilation. [7]
Polymorphisms in this gene have been associated with the perceived bitterness of sweetener acesulfame potassium. [8]
Dietdrinks or light drinks are sugar-free, artificially sweetened versions of carbonated beverages with virtually no calories. They are generally marketed toward health-conscious people, diabetics, athletes, and other people who want to lose weight, improve physical fitness, or reduce their sugar intake.
Aftertaste is the taste intensity of a food or beverage that is perceived immediately after that food or beverage is removed from the mouth. The aftertastes of different foods and beverages can vary by intensity and over time, but the unifying feature of aftertaste is that it is perceived after a food or beverage is either swallowed or spat out. The neurobiological mechanisms of taste signal transduction from the taste receptors in the mouth to the brain have not yet been fully understood. However, the primary taste processing area located in the insula has been observed to be involved in aftertaste perception.
TAS2R16 is a human gene that encodes for a receptor that may play a role in the perception of bitterness.
Taste receptor 2 member 38 is a protein that in humans is encoded by the TAS2R38 gene. TAS2R38 is a bitter taste receptor; varying genotypes of TAS2R38 influence the ability to taste both 6-n-propylthiouracil (PROP) and phenylthiocarbamide (PTC). Though it has often been proposed that varying taste receptor genotypes could influence tasting ability, TAS2R38 is one of the few taste receptors shown to have this function.
Taste receptor type 2 member 9 is a protein that in humans is encoded by the TAS2R9 gene.
Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene.
Taste receptor type 2 member 14 is a protein that in humans is encoded by the TAS2R14 gene.
Taste receptor type 1 member 2 is a protein that in humans is encoded by the TAS1R2 gene.
Taste receptor type 1 member 3 is a protein that in humans is encoded by the TAS1R3 gene. The TAS1R3 gene encodes the human homolog of mouse Sac taste receptor, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharin, and other sweeteners.
Taste receptor type 2 member 39 is a protein that in humans is encoded by the TAS2R39 gene.
Taste receptor type 2 member 40 is a protein that in humans is encoded by the TAS2R40 gene.
Taste receptor type 2 member 41 is a protein that in humans is encoded by the TAS2R41 gene.
Taste receptor type 2 member 43 is a protein that in humans is encoded by the TAS2R43 gene.
Taste receptor type 2 member 45 is a protein that in humans is encoded by the TAS2R45 gene.
Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.
Taste receptor type 2 member 30 is a protein that in humans is encoded by the TAS2R30 gene.
Taste receptor type 2 member 19 is a protein that in humans is encoded by the TAS2R19 gene. It seems to be involved in the perception of salt and bitter tastes.
Taste receptor type 2 member 20 is a protein that in humans is encoded by the TAS2R20 gene.
Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.
Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.