GPR33

GPR33
Identifiers
Aliases	GPR33 , G protein-coupled receptor 33 (gene/pseudogene), G protein-coupled receptor 33
External IDs	OMIM: 610118; MGI: 1277106; HomoloGene: 7345; GeneCards: GPR33; OMA:GPR33 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q12 Start 31,482,875 bp [1] End 31,488,039 bp [1]
Gene location (Mouse) Chr. Chromosome 12 (mouse) [2] Band 12|12 C1 Start 52,069,786 bp [2] End 52,074,846 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum white blood cell appendix monocyte lymph node tonsil urinary bladder left ventricle salivary gland Top expressed in lumbar subsegment of spinal cord right ventricle central gray substance of midbrain nucleus of stria terminalis sternocleidomastoid muscle upper arm triceps brachii muscle tracheobronchial tree mucosa of small intestine tibiofemoral joint More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity complement receptor activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process G protein-coupled receptor signaling pathway signal transduction complement receptor mediated signaling pathway inflammatory response phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration leukocyte migration cell chemotaxis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2856 14762 Ensembl ENSG00000214943 ENSMUSG00000035148 UniProt Q49SQ1 O88416 RefSeq (mRNA) NM_001197184 NM_008159 RefSeq (protein) NP_001184113 NP_001184113.2 NP_032185 Location (UCSC) Chr 14: 31.48 – 31.49 Mb Chr 12: 52.07 – 52.07 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 33 is a protein that in humans is encoded by the GPR33 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000214943 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035148 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Marchese A, Nguyen T, Malik P, Xu S, Cheng R, Xie Z, Heng HH, George SR, Kolakowski LF Jr, O'Dowd BF (Oct 1998). "Cloning genes encoding receptors related to chemoattractant receptors". Genomics. 50 (2): 281–6. doi:10.1006/geno.1998.5297. PMID   9653656.
6. "Entrez Gene: GPR33 G protein-coupled receptor 33".

Further reading

• Römpler H, Schulz A, Pitra C, et al. (2005). "The rise and fall of the chemoattractant receptor GPR33". J. Biol. Chem. 280 (35): 31068–75. doi: 10.1074/jbc.M503586200 . hdl: 11858/00-001M-0000-0010-0286-5 . PMID   15987686.