Galanin receptor 3 (GAL3) is a G-protein coupled receptor encoded by the GALR3 gene. [5]
Galanin receptor 3 (GAL3) is a G-protein coupled receptor encoded by the GALR3 gene. [5]
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [5]
The thyrotropin receptor is a receptor that responds to thyroid-stimulating hormone and stimulates the production of thyroxine (T4) and triiodothyronine (T3). The TSH receptor is a member of the G protein-coupled receptor superfamily of integral membrane proteins and is coupled to the Gs protein.
Galanin is a neuropeptide encoded by the GAL gene, that is widely expressed in the brain, spinal cord, and gut of humans as well as other mammals. Galanin signaling occurs through three G protein-coupled receptors.
The thromboxane receptor (TP) also known as the prostanoid TP receptor is a protein that in humans is encoded by the TBXA2R gene, The thromboxane receptor is one among the five classes of prostanoid receptors and was the first eicosanoid receptor cloned. The TP receptor derives its name from its preferred endogenous ligand thromboxane A2.
The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene.
The galanin receptor is a G protein-coupled receptor, or metabotropic receptor which binds galanin.
5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene.
Galanin receptor 1 (GAL1) is a G-protein coupled receptor encoded by the GALR1 gene.
5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family. The human gene is denoted as HTR1E.
Neuropeptide Y receptor type 2 (Y2R) is a member of the neuropeptide Y receptor family of G-protein coupled receptors, that in humans is encoded by the NPY2R gene.
Frizzled-1(Fz-1) is a protein that in humans is encoded by the FZD1 gene.
Galanin receptor 2, (GAL2) is a G-protein coupled receptor encoded by the GALR2 gene.
Neurotensin receptor type 2 is a protein that in humans is encoded by the NTSR2 gene.
Sphingosine-1-phosphate receptor 5 also known as S1PR5 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P5.
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
Lysophosphatidic acid receptor 5 also known as LPA5 is a protein that in humans is encoded by the LPAR5 gene. LPA5 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene.
Probable G-protein coupled receptor 151 is a protein that in humans is encoded by the GPR151 gene.
Adenylyl cyclase type 1 is an enzyme that in humans is encoded by the ADCY1 gene.
Olfactory receptor 1D5 is a protein that in humans is encoded by the OR1D5 gene. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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