GPR62

Last updated
GPR62
Identifiers
Aliases GPR62 , GPCR8, KPG_005, G protein-coupled receptor 62
External IDs OMIM: 606917 MGI: 3525078 HomoloGene: 50962 GeneCards: GPR62
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080865

NM_001159652

RefSeq (protein)

NP_543141

NP_001153124

Location (UCSC) Chr 3: 51.96 – 51.96 Mb Chr 9: 106.34 – 106.34 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene. [5] [6]

G protein–coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM] [6]

Related Research Articles

<span class="mw-page-title-main">GPR52</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.

<span class="mw-page-title-main">GPR160</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 160 is a protein that in humans is encoded by the GPR160 gene.

<span class="mw-page-title-main">GPR82</span> Protein-coding gene in humans

Probable G-protein coupled receptor 82 is a protein that in humans is encoded by the GPR82 gene.

<span class="mw-page-title-main">GPR63</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 63 is a protein that in humans is encoded by the GPR63 gene.

<span class="mw-page-title-main">GPR174</span> Protein-coding gene in humans

Probable G-protein coupled receptor 174 is a protein that in humans is encoded by the GPR174 gene.

<span class="mw-page-title-main">GPR146</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 146 is a protein that in humans is encoded by the GPR146 gene. It has been identified as a possible receptor for C-peptide.

<span class="mw-page-title-main">MRGPRD</span> Protein-coding gene in the species Homo sapiens

Mas-related G-protein coupled receptor member D is a protein that in humans is encoded by the MRGPRD gene.

<span class="mw-page-title-main">GPR113</span> Protein-coding gene in the species Homo sapiens

GPR113 is a gene that encodes the Probable G-protein coupled receptor 113 protein.

<span class="mw-page-title-main">GPR156</span> Protein-coding gene in the species Homo sapiens

GPR156, is a human gene which encodes a G protein-coupled receptor belonging to metabotropic glutamate receptor subfamily. By sequence homology, this gene was proposed as being a possible GABAB receptor subunit, however when expressed in cells alone or with other GABAB subunits, no response to GABAB ligands could be detected. Therefore, the function of this protein remains to be elucidated. In vitro studies on GPR156 constitutive activity revealed a high level of basal activation and coupling with members of the Gi/Go heterotrimeric G protein family.

<span class="mw-page-title-main">GPR115</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene.

<span class="mw-page-title-main">GPR111</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 111 is a protein that in humans is encoded by the GPR111 gene.

<span class="mw-page-title-main">GPR110</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 110 is a protein that in humans is encoded by the GPR110 gene. This gene encodes a member of the adhesion-GPCR receptor family. Family members are characterized by an extended extracellular region with a variable number of N-terminal protein modules coupled to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

<span class="mw-page-title-main">GPR150</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.

<span class="mw-page-title-main">GPR141</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 141 is a protein that in humans is encoded by the GPR141 gene.

<span class="mw-page-title-main">GPR153</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.

<span class="mw-page-title-main">GPR152</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 152 is a protein that in humans is encoded by the GPR152 gene.

<span class="mw-page-title-main">GPR161</span> Protein-coding gene in the species Homo sapiens

G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene.

<span class="mw-page-title-main">GPR139</span> Protein-coding gene in the species Homo sapiens

G-protein coupled receptor 139 (GPC139) is a protein that in humans is encoded by the GPR139 gene. Recent research ('21) has shown that mice with loss of GCP139 experience schizophrenia-like symptomatology that is rescued with the dopamine receptor antagonist haloperidol and the μ-opioid receptor antagonist naltrexone; as well, the recently developed, potent, and GPR139 receptor selective agonist TAK-041 is currently undergoing trials to gauge the efficacy for treating psychiatric conditions such as major depressive disorder and the negative symptoms of schizophrenia.

<span class="mw-page-title-main">GPR151</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 151 is a protein that in humans is encoded by the GPR151 gene.

<span class="mw-page-title-main">GPR61</span> Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000180929 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000091735 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID   11165367.
  6. 1 2 "Entrez Gene: GPR62 G protein-coupled receptor 62".

Further reading