GPR176

GPR176
Identifiers
Aliases	GPR176 , HB-954, G protein-coupled receptor 176
External IDs	OMIM: 612183; MGI: 2685858; HomoloGene: 5226; GeneCards: GPR176; OMA:GPR176 - orthologs
Gene location (Human) Chr. Chromosome 15 (human) [1] Band 15q14-q15.1 Start 39,799,008 bp [1] End 39,920,266 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 E5 Start 118,107,591 bp [2] End 118,203,900 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium ascending aorta saphenous vein right coronary artery Descending thoracic aorta pons cerebellar hemisphere right hemisphere of cerebellum gonad tibial arteries Top expressed in calvaria stroma of bone marrow suprachiasmatic nucleus substantia nigra arcuate nucleus supraoptic nucleus subiculum lateral hypothalamus paraventricular nucleus of hypothalamus otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane integral component of plasma membrane membrane plasma membrane Biological process signal transduction chemical synaptic transmission G protein-coupled receptor signaling pathway circadian behavior rhythmic process adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11245 381413 Ensembl ENSG00000166073 ENSMUSG00000040133 UniProt Q14439 Q80WT4 RefSeq (mRNA) NM_001271854 NM_001271855 NM_007223 NM_201367 RefSeq (protein) NP_001258783 NP_001258784 NP_009154 NP_958755 Location (UCSC) Chr 15: 39.8 – 39.92 Mb Chr 2: 118.11 – 118.2 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 176 is a protein that in humans is encoded by the GPR176 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000166073 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000040133 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hata S, Emi Y, Iyanagi T, Osumi T (Apr 1995). "cDNA cloning of a putative G protein-coupled receptor from brain". Biochim Biophys Acta. 1261 (1): 121–5. doi:10.1016/0167-4781(95)00002-x. PMID   7893747.
6. "Entrez Gene: GPR176 G protein-coupled receptor 176".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.