Neuropeptide FF receptor 1

NPFFR1
Identifiers
Aliases	NPFFR1 , GPR147, NPFF1, NPFF1R1, OT7T022, neuropeptide FF receptor 1
External IDs	OMIM: 607448; MGI: 2685082; HomoloGene: 23348; GeneCards: NPFFR1; OMA:NPFFR1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human) [1] Band 10q22.1 Start 70,247,329 bp [1] End 70,284,004 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 B4 Start 61,431,271 bp [2] End 61,464,344 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in dorsal motor nucleus of vagus nerve cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum spinal cord nucleus accumbens C1 segment occipital lobe hypothalamus tibial nerve Top expressed in dentate gyrus of hippocampal formation granule cell hypothalamus hippocampus proper superior frontal gyrus primary visual cortex cerebellar cortex mesencephalon striatum of neuraxis olfactory bulb spermatid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptide binding signal transducer activity G protein-coupled receptor activity neuropeptide receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane cilium Biological process cellular response to hormone stimulus signal transduction response to peptide neuropeptide signaling pathway G protein-coupled receptor signaling pathway biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64106 237362 Ensembl ENSG00000148734 ENSMUSG00000020090 UniProt Q9GZQ6 E9Q468 RefSeq (mRNA) NM_022146 NM_001177511 RefSeq (protein) NP_071429 NP_001170982 Location (UCSC) Chr 10: 70.25 – 70.28 Mb Chr 10: 61.43 – 61.46 Mb PubMed search [3] [4]
Wikidata
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Neuropeptide FF receptor 1, also known as NPFF1 and formerly as GPR147, is a human protein, encoded by the NPFFR1 gene. ^[5]

See also

• Neuropeptide FF receptor

References

1. GRCh38: Ensembl release 89: ENSG00000148734 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020090 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: NPFFR1 neuropeptide FF receptor 1".

Further reading

• Bonini JA, Jones KA, Adham N, et al. (2001). "Identification and characterization of two G protein-coupled receptors for neuropeptide FF". J. Biol. Chem. 275 (50): 39324–31. doi: 10.1074/jbc.M004385200 . PMID   11024015.
• Hinuma S, Shintani Y, Fukusumi S, et al. (2000). "New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals". Nat. Cell Biol. 2 (10): 703–8. doi:10.1038/35036326. PMID   11025660. S2CID   2580390.

External links

• "Neuropeptide FF Receptors: NPFF1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-09.