GPR87

GPR87
Identifiers
Aliases	GPR87 , GPR95, KPG_002, FKSG78, G protein-coupled receptor 87
External IDs	OMIM: 606379; MGI: 1934133; HomoloGene: 13021; GeneCards: GPR87; OMA:GPR87 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q25.1 Start 151,294,086 bp [1] End 151,316,820 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 D Start 59,086,344 bp [2] End 59,102,525 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in hair follicle skin of arm gingival epithelium oral cavity skin of thigh skin of abdomen cervix epithelium vulva amniotic fluid epithelium of nasopharynx Top expressed in esophagus hair follicle skin of external ear skin of back cornea skin of abdomen lip conjunctival fornix transitional epithelium of urinary bladder condyle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled purinergic nucleotide receptor activity G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway negative regulation of adenylate cyclase activity signal transduction G protein-coupled purinergic nucleotide receptor signaling pathway biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 53836 84111 Ensembl ENSG00000138271 ENSMUSG00000051431 UniProt Q9BY21 Q99MT7 RefSeq (mRNA) NM_023915 NM_001302203 NM_032399 RefSeq (protein) NP_076404 NP_001289132 Location (UCSC) Chr 3: 151.29 – 151.32 Mb Chr 3: 59.09 – 59.1 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 87 is a protein that in humans is encoded by the GPR87 gene. ^{[5] [6]}

G protein-coupled receptors play a role in cell communication. They are characterized by an extracellular N terminus, 7 transmembrane regions, and an intracellular C terminus.[supplied by OMIM] ^[6]

References

1. GRCh38: Ensembl release 89: ENSG00000138271 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051431 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors". J Mol Biol. 307 (3): 799–813. doi:10.1006/jmbi.2001.4520. PMID   11273702.
6. "Entrez Gene: GPR87 G protein-coupled receptor 87".

Further reading

• Lee DK, Nguyen T, Lynch KR, et al. (2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID   11574155.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.