GPR144

ADGRD2
Identifiers
Aliases	ADGRD2 , PGR24, GPR144, adhesion G protein-coupled receptor D2
External IDs	HomoloGene: 130029; GeneCards: ADGRD2; OMA:ADGRD2 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.3 Start 124,450,451 bp [1] End 124,478,589 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland triceps brachii muscle vena cava right ventricle dorsal motor nucleus of vagus nerve pituitary gland anterior pituitary lateral nuclear group of thalamus inferior olivary nucleus cerebellar vermis n/a More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 347088 n/a Ensembl ENSG00000180264 n/a UniProt n a n/a RefSeq (mRNA) NM_001161808 NM_182611 NM_001395425 n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 9: 124.45 – 124.48 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene. ^{[3] [4]} This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000180264 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: GPR144 G protein-coupled receptor 144".
4. Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi: 10.1016/S0014-5793(02)03574-3 . PMID   12435584. S2CID   7449692.
5. Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN   978-1-4419-7912-4.
6. Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC   3321182 . PMID   22333914.

Further reading

• Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi: 10.1073/pnas.0230374100 . PMC   153653 . PMID   12679517.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.
• Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID   15203201.