GPR144

Last updated
ADGRD2
Identifiers
Aliases ADGRD2 , PGR24, GPR144, adhesion G protein-coupled receptor D2
External IDs HomoloGene: 130029 GeneCards: ADGRD2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001161808
NM_182611

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC) Chr 9: 124.45 – 124.48 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene. [3] [4] This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain. [5] [6]

Related Research Articles

Latrophilin 1

Latrophilin 1 is a protein that in humans is encoded by the ADGRL1 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Latrophilin 3

Latrophilin 3 is a protein that in humans is encoded by the ADGRL3 gene.

GPR124

Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR126

G protein-coupled receptor 126 also known as VIGR and DREG is a protein encoded by the ADGRG6 gene. GPR126 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR135

Probable G-protein coupled receptor 135 is a protein that in humans is encoded by the GPR135 gene.

GPR123

Probable G-protein coupled receptor 123 is a protein that in humans is encoded by the GPR123 gene. It is a member of the adhesion-GPCR family of receptors. Family members are normally characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR128

G protein-coupled receptor 128 is a protein encoded by the ADGRG7 gene. GPR128 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR112

G protein-coupled receptor 112 is a protein encoded by the ADGRG4 gene. GPR112 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR113

GPR113 is a gene that encodes the Probable G-protein coupled receptor 113 protein.

GPR125

Probable G-protein coupled receptor 125 is a protein that in humans is encoded by the GPR125 gene.

GPR114

G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR115

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene.

GPR116

Probable G-protein coupled receptor 116 is a protein that in humans is encoded by the GPR116 gene. GPR116 has now been shown to play an essential role in the regulation of lung surfactant homeostasis.

GPR97

G-protein coupled receptor 97 also known as adhesion G protein-coupled receptor G3 (ADGRG3) is a protein that in humans is encoded by the ADGRG3 gene. GPR97 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR111

Probable G-protein coupled receptor 111 is a protein that in humans is encoded by the GPR111 gene.

GPR110

Probable G-protein coupled receptor 110 is a protein that in humans is encoded by the GPR110 gene. This gene encodes a member of the adhesion-GPCR receptor family. Family members are characterized by an extended extracellular region with a variable number of N-terminal protein modules coupled to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

GPR133

Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.

GPR141

Probable G-protein coupled receptor 141 is a protein that in humans is encoded by the GPR141 gene.

GPR120

G-protein coupled receptor 120 is a protein that in humans is encoded by the GPR120 gene.

GPR142

Probable G-protein coupled receptor 142 is a protein that in humans is encoded by the GPR142 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000180264 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: GPR144 G protein-coupled receptor 144".
  4. Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi: 10.1016/S0014-5793(02)03574-3 . PMID   12435584. S2CID   7449692.
  5. Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN   978-1-4419-7912-4.
  6. Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC   3321182 . PMID   22333914.

Further reading