GPR160

GPR160
Identifiers
Aliases	GPR160 , GPCR1, GPCR150, G protein-coupled receptor 160
External IDs	MGI: 1919112; HomoloGene: 8659; GeneCards: GPR160; OMA:GPR160 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q26.2 Start 170,037,995 bp [1] End 170,085,392 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 A3 Start 30,910,099 bp [2] End 30,951,341 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum mucosa of sigmoid colon rectum corpus epididymis duodenum bone marrow jejunal mucosa bone marrow cells mucosa of transverse colon trabecular bone Top expressed in spermatocyte spermatid seminiferous tubule lens jejunum epithelium of lens right kidney granulocyte duodenum skin of abdomen More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane receptor complex membrane plasma membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26996 71862 Ensembl ENSG00000173890 ENSMUSG00000037661 UniProt Q9UJ42 Q3U3F9 RefSeq (mRNA) NM_014373 NM_001134385 NM_001134386 NM_001286994 NM_001286995 NM_001286996 NM_027965 NM_001357144 RefSeq (protein) NP_055188 NP_001127857 NP_001127858 NP_001273923 NP_001273924 NP_001273925 NP_082241 NP_001344073 Location (UCSC) Chr 3: 170.04 – 170.09 Mb Chr 3: 30.91 – 30.95 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 160 is a protein that in humans is encoded by the GPR160 gene. ^{[5] [6]} It has been identified as the receptor for Cocaine- and amphetamine-regulated transcript, also known as CART. ^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000173890 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000037661 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S (Jun 2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. Bibcode:2002FEBSL.520...97T. doi:10.1016/S0014-5793(02)02775-8. PMID   12044878. S2CID   7116392.
6. "Entrez Gene: GPR160 G protein-coupled receptor 160".
7. Yosten, Gina L. C.; Harada, Caron M.; Haddock, Chris; Giancotti, Luigino Antonio; Kolar, Grant R.; Patel, Ryan; Guo, Chun; Chen, Zhoumou; Zhang, Jinsong; Doyle, Timothy M.; Dickenson, Anthony H.; Samson, Willis K.; Salvemini, Daniela (1 May 2020). "GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents". The Journal of Clinical Investigation. 130 (5): 2587–2592. doi:10.1172/JCI133270. PMC   7190928 . PMID   31999650.

Further reading

• Conklin D, Yee DP, Millar R, et al. (2001). "Mining of assembled expressed sequence tag (EST) data for protein families: application to the G protein-coupled receptor superfamily". Brief. Bioinformatics. 1 (1): 93–9. doi: 10.1093/bib/1.1.93 . PMID   11466977.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.