GPR85

GPR85
Identifiers
Aliases	GPR85 , SREB, SREB2, G protein-coupled receptor 85
External IDs	OMIM: 605188 MGI: 1927851 HomoloGene: 10355 GeneCards: GPR85
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q31.1 Start 113,078,331 bp [1] End 113,087,778 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 A1 Start 13,834,457 bp [2] End 13,839,941 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell caudate nucleus putamen dorsolateral prefrontal cortex ganglionic eminence prefrontal cortex nucleus accumbens Brodmann area 23 hippocampus proper Brodmann area 9 Top expressed in barrel cortex Region I of hippocampus proper piriform cortex ventromedial nucleus substantia nigra temporal lobe facial motor nucleus habenula subiculum amygdala More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity protein binding signal transducer activity Cellular component integral component of membrane endoplasmic reticulum membrane plasma membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54329 64450 Ensembl ENSG00000164604 ENSMUSG00000048216 UniProt P60893 P60894 RefSeq (mRNA) NM_001146265 NM_001146266 NM_001146267 NM_018970 NM_145066 NM_001330666 NM_001330667 RefSeq (protein) NP_001139737 NP_001139738 NP_001139739 NP_061843 NP_001317595 NP_001317596 NP_659503 Location (UCSC) Chr 7: 113.08 – 113.09 Mb Chr 6: 13.83 – 13.84 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 85 is a protein that in humans is encoded by the GPR85 gene. ^{[5] [6] [7]}

See also

• SREB

References

1. GRCh38: Ensembl release 89: ENSG00000164604 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048216 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hellebrand S, Schaller HC, Wittenberger T (Nov 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochim Biophys Acta. 1493 (1–2): 269–72. doi:10.1016/s0167-4781(00)00182-2. PMID   10978537.
6. Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID   10833454.
7. "Entrez Gene: GPR85 G protein-coupled receptor 85".

Further reading

• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi: 10.1101/gr.8.11.1097 . PMID   9847074.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Jeon J, Kim C, Sun W, et al. (2002). "Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor". Biochem. Biophys. Res. Commun. 298 (4): 613–8. doi:10.1016/S0006-291X(02)02515-9. PMID   12408996.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Matsumoto M, Beltaifa S, Weickert CS, et al. (2005). "A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain". Brain Res. Mol. Brain Res. 138 (1): 58–69. doi:10.1016/j.molbrainres.2005.04.002. PMID   15893849.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.