GPR85

GPR85
Identifiers
Aliases	GPR85 , SREB, SREB2, G protein-coupled receptor 85
External IDs	OMIM: 605188; MGI: 1927851; HomoloGene: 10355; GeneCards: GPR85; OMA:GPR85 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q31.1 Start 113,078,331 bp [1] End 113,087,778 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 A1 Start 13,834,457 bp [2] End 13,839,941 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell caudate nucleus primary visual cortex putamen dorsolateral prefrontal cortex ganglionic eminence prefrontal cortex lateral nuclear group of thalamus nucleus accumbens Brodmann area 23 Top expressed in barrel cortex Rostral migratory stream Region I of hippocampus proper piriform cortex ventromedial nucleus substantia nigra temporal lobe facial motor nucleus lobe of cerebellum habenula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity protein binding signal transducer activity Cellular component integral component of membrane endoplasmic reticulum membrane plasma membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54329 64450 Ensembl ENSG00000164604 ENSMUSG00000048216 UniProt P60893 P60894 RefSeq (mRNA) NM_001146265 NM_001146266 NM_001146267 NM_018970 NM_145066 NM_001330666 NM_001330667 RefSeq (protein) NP_001139737 NP_001139738 NP_001139739 NP_061843 NP_001317595 NP_001317596 NP_659503 Location (UCSC) Chr 7: 113.08 – 113.09 Mb Chr 6: 13.83 – 13.84 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 85 is a protein that in humans is encoded by the GPR85 gene. ^{[5] [6] [7]}

See also

• SREB

References

1. GRCh38: Ensembl release 89: ENSG00000164604 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048216 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hellebrand S, Schaller HC, Wittenberger T (September 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1493 (1–2): 269–272. doi:10.1016/s0167-4781(00)00182-2. PMID   10978537.
6. Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, et al. (June 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochemical and Biophysical Research Communications. 272 (2): 576–582. doi:10.1006/bbrc.2000.2829. PMID   10833454.
7. "Entrez Gene: GPR85 G protein-coupled receptor 85".

Further reading

• The Sanger Centre, The Washington University Genome Sequencing Center (November 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–1108. doi: 10.1101/gr.8.11.1097 . PMID   9847074.
• Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, et al. (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–292. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Jeon J, Kim C, Sun W, Chung H, Park SH, Kim H (November 2002). "Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor". Biochemical and Biophysical Research Communications. 298 (4): 613–618. doi:10.1016/S0006-291X(02)02515-9. PMID   12408996.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, et al. (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Matsumoto M, Beltaifa S, Weickert CS, Herman MM, Hyde TM, Saunders RC, et al. (July 2005). "A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain". Brain Research. Molecular Brain Research. 138 (1): 58–69. doi:10.1016/j.molbrainres.2005.04.002. PMID   15893849.
• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, et al. (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, et al. (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415 –D418. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.