GPR141

GPR141
Identifiers
Aliases	GPR141 , PGR13, G protein-coupled receptor 141
External IDs	OMIM: 609045 MGI: 2672983 HomoloGene: 18771 GeneCards: GPR141
Gene location (Human)
Chr.	Chromosome 7 (human)
End	37,833,788 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	20,008,427 bp
RNA expression pattern
	Top expressed in
	monocyte; ; bone marrow; ; blood; ; bone marrow cells; ; appendix; ; gallbladder; ; spleen; ; smooth muscle tissue; ; placenta; ; lymph node;
	Top expressed in
	ovary; ; bone marrow; ; spleen; ; zone of skin; ; ileum; ; jejunum; ; placenta; ; lung; ; lip; ; colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity ; G protein-coupled receptor activity ;
Cellular component	membrane ; integral component of membrane ; plasma membrane ;
Biological process	signal transduction ; G protein-coupled receptor signaling pathway ;
	Sources:Amigo / QuickGO
Orthologs
	353345
	353346
	ENSG00000187037
	ENSMUSG00000053101
	Q7Z602
	Q7TQP0
	NM_181791 ; NM_001329993 ; NM_001329994 ; NM_001381946
	NM_181754
	NP_001316922 ; NP_001316923 ; NP_861456 ; NP_001368875
	NP_861419
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 08, 2023

Probable G-protein coupled receptor 141 is a protein that in humans is encoded by the GPR141 gene.^[5]^[6]^[7]

GPR141 is a member of the rhodopsin family of G protein-coupled receptors (GPRs).^[6]^[7]

Related Research Articles

Probable G-protein coupled receptor 20 is a protein that in humans is encoded by the GPR20 gene.

Probable G-protein coupled receptor 135 is a protein that in humans is encoded by the GPR135 gene.

Probable G-protein coupled receptor 146 is a protein that in humans is encoded by the GPR146 gene. It has been identified as a possible receptor for C-peptide.

Mas-related G-protein coupled receptor member D is a protein that in humans is encoded by the MRGPRD gene.

Mas-related G-protein coupled receptor member E is a protein that in humans is encoded by the MRGPRE gene.

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene.

Probable G-protein coupled receptor 111 is a protein that in humans is encoded by the GPR111 gene.

Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.

Relaxin/insulin-like family peptide receptor 4, also known as RXFP4, is a human G-protein coupled receptor.

Probable G-protein coupled receptor 149 is a protein that in humans is encoded by the GPR149 gene.

Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.

Probable G-protein coupled receptor 152 is a protein that in humans is encoded by the GPR152 gene.

G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene.

Probable G-protein coupled receptor 162 is a protein that in humans is encoded by the GPR162 gene.

G-protein coupled receptor 139 (GPC139) is a protein that in humans is encoded by the GPR139 gene. Recent research ('21) has shown that mice with loss of GCP139 experience schizophrenia-like symptomatology that is rescued with the dopamine receptor antagonist haloperidol and the μ-opioid receptor antagonist naltrexone; as well, the recently developed, potent, and GPR139 receptor selective agonist TAK-041 is currently undergoing trials to gauge the efficacy for treating psychiatric conditions such as major depressive disorder and the negative symptoms of schizophrenia.

Probable G-protein coupled receptor 151 is a protein that in humans is encoded by the GPR151 gene.

Probable G-protein coupled receptor 142 is a protein that in humans is encoded by the GPR142 gene.

G protein-coupled receptor 148, also known as GPR148, is a human orphan receptor from GPCR superfamily. It is expressed primarily in nervous system and testis. Is may be implicated in prostate cancer.

Mas-related G-protein coupled receptor member G (MRGG) also known as G-protein coupled receptor 169 (GPR169) is a protein that in humans is encoded by the MRGPRG gene. MRGG is an orphan G-protein coupled receptor.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000187037 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053101 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, et al. (April 2003). "The G protein-coupled receptor repertoires of human and mouse". Proceedings of the National Academy of Sciences of the United States of America. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi: 10.1073/pnas.0230374100 . PMC 153653 . PMID 12679517.
1 2 Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB (November 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Letters. 554 (3): 381–8. doi: 10.1016/S0014-5793(03)01196-7 . PMID 14623098. S2CID 11563502.
1 2 "Entrez Gene: GPR141 G protein-coupled receptor 141".

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000187037 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053101 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12679517-5] Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, et al. (April 2003). "The G protein-coupled receptor repertoires of human and mouse". Proceedings of the National Academy of Sciences of the United States of America. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi: 10.1073/pnas.0230374100 . PMC 153653 . PMID 12679517.

[Fredriksson_2003-6] 1 2 Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB (November 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Letters. 554 (3): 381–8. doi: 10.1016/S0014-5793(03)01196-7 . PMID 14623098. S2CID 11563502.

[entrez-7] 1 2 "Entrez Gene: GPR141 G protein-coupled receptor 141".

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