P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene. [3] [4]
The product of this gene, P2Y11, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occurring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [4]
P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as adenosine triphosphate, adenosine diphosphate, uridine triphosphate, uridine diphosphate and UDP-glucose.To date, 8 P2Y receptors have been cloned in humans: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14.
Leukotriene B4 receptor 1 is a protein that in humans is encoded by the LTB4R gene.
Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334.
Regulator of G-protein signaling 2 is a protein that in humans is encoded by the RGS2 gene. It is part of a larger family of RGS proteins that control signalling through G-protein coupled receptors (GPCR).
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
P2X purinoceptor 1, also ATP receptor, is a protein that in humans is encoded by the P2RX1 gene.
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.
Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene. LPA4 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.
Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
Chemokine-binding protein 2 is a protein that in humans is encoded by the CCBP2 gene.
P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.
CD81 molecule, also known as CD81, is a protein which in humans is encoded by the CD81 gene. It is also known as 26 kDa cell surface protein, TAPA-1, and Tetraspanin-28 (Tspan-28).
Adenylyl cyclase type 5 is an enzyme that in humans is encoded by the ADCY5 gene.
Suppressor of SWI4 1 homolog is a protein that in humans is encoded by the PPAN gene.
Adenylyl cyclase type 7 is an enzyme that in humans is encoded by the ADCY7 gene.
Guanine nucleotide-binding protein G(T) subunit gamma-T1 is a protein that in humans is encoded by the GNGT1 gene. Either GNGT1 or GNGT2 is the gamma subunit (Gγ) of the Gβγ part of transducin, a heterotrimeric G-protein naturally expressed in vertebrate retina rod and cone cells. GNGT1 only occurs in rod cells, and GNGT2 only occurs in cone cells, with a different alpha (Gα) subunit.
P2X purinoceptor 2 is a protein that in humans is encoded by the P2RX2 gene.
Prostaglandin F2 receptor negative regulator is a protein that in humans is encoded by the PTGFRN gene. PTGFRN has also been designated as CD315.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.