GPR115

ADGRF4
Identifiers
Aliases	ADGRF4 , PGR18, GPR115, adhesion G protein-coupled receptor F4
External IDs	OMIM: 614268; MGI: 1925499; HomoloGene: 51953; GeneCards: ADGRF4; OMA:ADGRF4 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p12.3 Start 47,685,864 bp [1] End 47,722,021 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B3 Start 42,967,782 bp [2] End 43,003,175 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen skin of leg skin of arm gingival epithelium human penis right uterine tube amniotic fluid skin of thigh vagina oral cavity Top expressed in decidua skin of external ear gastrula lip molar skin of abdomen skin of back embryo epidermis hair follicle More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane membrane Biological process G protein-coupled receptor signaling pathway cell surface receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 221393 78249 Ensembl ENSG00000153294 ENSMUSG00000023918 UniProt Q8IZF3 Q9D2L6 RefSeq (mRNA) NM_153838 NM_001347855 NM_001289499 NM_001289500 NM_001289501 NM_030067 RefSeq (protein) NP_001334784 NP_722580 NP_001276428 NP_001276429 NP_001276430 NP_084343 Location (UCSC) Chr 6: 47.69 – 47.72 Mb Chr 17: 42.97 – 43 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000153294 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000023918 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi: 10.1016/S0014-5793(02)03574-3 . PMID   12435584. S2CID   7449692.
6. "Entrez Gene: GPR115 G protein-coupled receptor 115".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.
• Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi: 10.1073/pnas.0230374100 . PMC   153653 . PMID   12679517.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID   15203201.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.