TAAR9 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | TAAR9 , TA3, TAR3, TAR9, TRAR3, trace amine associated receptor 9 (gene/pseudogene), trace amine associated receptor 9 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 608282; MGI: 3527454; HomoloGene: 65286; GeneCards: TAAR9; OMA:TAAR9 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Trace amine-associated receptor 9 is a protein that in humans is encoded by the TAAR9 gene. [5] [6]
TAAR9 is a member of a large family of rhodopsin G protein–coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM] [6] N-Methyl piperidine is a ligand of TAAR9 associated with aversive behavior in mice. N,N-dimethylcyclohexylamine is an additional binding agonist that also activaes TAAR7 variants. [7] [8]
TAAR9 gene deletion in rats leads to significantly decreased low-density lipoprotein cholesterol levels in the blood. [9]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.