GPR179

GPR179
Identifiers
Aliases	GPR179 , CSNB1E, GPR158L, GPR158L1, G protein-coupled receptor 179
External IDs	OMIM: 614515 MGI: 2443409 HomoloGene: 34917 GeneCards: GPR179
Gene location (Human)
Chr.	Chromosome 17 (human)
End	38,343,956 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	97,242,903 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; superior frontal gyrus; ; sural nerve; ; Brodmann area 9; ; skeletal muscle tissue; ; hypothalamus; ; nucleus accumbens; ; cerebellum; ; cerebellar cortex; ; cerebellar hemisphere;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity ; signal transducer activity ;
Cellular component	integral component of membrane ; plasma membrane ; membrane ;
Biological process	G protein-coupled receptor signaling pathway ; signal transduction ; visual perception ; response to stimulus ;
	Sources:Amigo / QuickGO
Orthologs
	440435
	217143
	ENSG00000276469 ; ENSG00000277399
	ENSMUSG00000070337
	Q6PRD1
	E9PY61
	NM_001004334
	NM_001081220 ; NM_175453
	NP_001004334
	NP_001074689
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated June 20, 2022

Probable G-protein coupled receptor 179 is a protein that in humans is encoded by the GPR179 gene.^[5]

Clinical relevance

Mutations in this gene have been associated to cases of congenital stationary Night Blindness.^[6]

Related Research Articles

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G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene.

Probable G-protein coupled receptor 19 is a protein that in humans is encoded by the GPR19 gene.

Probable G-protein coupled receptor 20 is a protein that in humans is encoded by the GPR20 gene.

Lysophosphatidic acid receptor 4 also known as LPA₄ is a protein that in humans is encoded by the LPAR4 gene. LPA₄ is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Probable G-protein coupled receptor 25 is a protein that in humans is encoded by the GPR25 gene.

Probable G-protein coupled receptor 26 is a protein that in humans is encoded by the GPR26 gene. GPR26 expression is found to peak perinatally, when the visual system is first challenged, and contains a 53 kb LD-block enriched for association with introgressed Neanderthal-derived SNPs. Additionally, it is known to form oligomeric structures with the 5-HT1a receptor.

Probable G-protein coupled receptor 33 is a protein that in humans is encoded by the GPR33 gene.

Probable G-protein coupled receptor 34 is a protein that in humans is encoded by the GPR34 gene.

Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Hydroxycarboxylic acid receptor 1 (HCA₁), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1 gene. HCA₁, like the other hydroxycarboxylic acid receptors HCA₂ and HCA₃, is a G_i/o-coupled G protein-coupled receptor (GPCR). The primary endogenous agonist of HCA₁ is lactic acid (and its conjugate base, lactate).

Probable G-protein coupled receptor 171 is a protein that in humans is encoded by the GPR171 gene.

Lysophosphatidic acid receptor 5 also known as LPA₅ is a protein that in humans is encoded by the LPAR5 gene. LPA₅ is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Probable G-protein coupled receptor 135 is a protein that in humans is encoded by the GPR135 gene.

Probable G-protein coupled receptor 157 is a protein that in humans is encoded by the GPR157 gene.

Probable G-protein coupled receptor 101 is a protein that in humans is encoded by the GPR101 gene.

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.

Glutamate receptor, metabotropic 6, also known as GRM6 or mGluR6, is a protein which in humans is encoded by the GRM6 gene.

Probable G-protein coupled receptor 139 is a protein that in humans is encoded by the GPR139 gene.

Trace amine-associated receptor 9 is a protein that in humans is encoded by the TAAR9 gene.

References

1 2 3 ENSG00000277399 GRCh38: Ensembl release 89: ENSG00000276469, ENSG00000277399 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070337 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: GPR179 G protein-coupled receptor 179".
↑ Audo I, Bujakowska K, Orhan E, Poloschek CM, Defoort-Dhellemmes S, Drumare I, Kohl S, Luu TD, Lecompte O, Zrenner E, Lancelot ME, Antonio A, Germain A, Michiels C, Audier C, Letexier M, Saraiva JP, Leroy BP, Munier FL, Mohand-Saïd S, Lorenz B, Friedburg C, Preising M, Kellner U, Renner AB, Moskova-Doumanova V, Berger W, Wissinger B, Hamel CP, Schorderet DF, De Baere E, Sharon D, Banin E, Jacobson SG, Bonneau D, Zanlonghi X, Le Meur G, Casteels I, Koenekoop R, Long VW, Meire F, Prescott K, de Ravel T, Simmons I, Nguyen H, Dollfus H, Poch O, Léveillard T, Nguyen-Ba-Charvet K, Sahel JA, Bhattacharya SS, Zeitz C (Feb 10, 2012). "Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness". American Journal of Human Genetics. 90 (2): 321–30. doi:10.1016/j.ajhg.2011.12.007. PMC 3276675 . PMID 22325361.

GPR179

Contents

Clinical relevance

Related Research Articles

References

Further reading