MRGPRD

MRGPRD
Identifiers
Aliases	MRGPRD , MRGD, TGR7, MAS related GPR family member D
External IDs	OMIM: 607231 MGI: 3033142 HomoloGene: 18893 GeneCards: MRGPRD
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q13.3 Start 68,980,021 bp [1] End 68,980,986 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 F5 Start 144,868,572 bp [2] End 144,877,823 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa left uterine tube popliteal artery right coronary artery cerebellum smooth muscle tissue cerebellar cortex cerebellar hemisphere urinary bladder ascending aorta Top expressed in spinal cord pons anterior horn of spinal cord diencephalon hypothalamus More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane extracellular space integral component of plasma membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116512 211578 Ensembl ENSG00000172938 ENSMUSG00000051207 UniProt Q8TDS7 Q91ZB8 RefSeq (mRNA) NM_198923 NM_203490 RefSeq (protein) NP_944605 NP_987075 Location (UCSC) Chr 11: 68.98 – 68.98 Mb Chr 7: 144.87 – 144.88 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mas-related G-protein coupled receptor member D is a protein that in humans is encoded by the MRGPRD gene. ^{[5] [6] [7]}

See also

• MAS1 oncogene

References

1. GRCh38: Ensembl release 89: ENSG00000172938 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051207 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell. 106 (5): 619–32. doi: 10.1016/S0092-8674(01)00483-4 . PMID   11551509. S2CID   14119088.
6. Zylka MJ, Dong X, Southwell AL, Anderson DJ (Aug 2003). "Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family". Proc Natl Acad Sci U S A. 100 (17): 10043–8. Bibcode:2003PNAS..10010043Z. doi: 10.1073/pnas.1732949100 . PMC   187757 . PMID   12909716.
7. "Entrez Gene: MRGPRD MAS-related GPR, member D".

Further reading

• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi: 10.1016/S0014-5793(02)02775-8 . PMID   12044878. S2CID   7116392.
• Shinohara T, Harada M, Ogi K, et al. (2004). "Identification of a G protein-coupled receptor specifically responsive to beta-alanine". J. Biol. Chem. 279 (22): 23559–64. doi: 10.1074/jbc.M314240200 . PMID   15037633.