P2RY4

Last updated
P2RY4
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases P2RY4 , NRU, P2P, P2Y4, UNR, pyrimidinergic receptor P2Y4
External IDs OMIM: 300038 MGI: 1926594 HomoloGene: 20568 GeneCards: P2RY4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002565

NM_020621

RefSeq (protein)

NP_002556

NP_065646

Location (UCSC) Chr X: 70.26 – 70.26 Mb Chr X: 99.63 – 99.64 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene. [5] [6]

Contents

The product of this gene, P2Y4, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [6]

See also

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000186912 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000044359 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Communi D, Pirotton S, Parmentier M, Boeynaems JM (Feb 1996). "Cloning and functional expression of a human uridine nucleotide receptor". J Biol Chem. 270 (52): 30849–52. doi: 10.1074/jbc.270.52.30849 . PMID   8537336.
  6. 1 2 "Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.