TAS2R60

TAS2R60
Identifiers
Aliases	TAS2R60 , T2R56, T2R60, taste 2 receptor member 60
External IDs	OMIM: 613968 MGI: 2681302 HomoloGene: 52230 GeneCards: TAS2R60
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q35 Start 143,443,453 bp [1] End 143,444,409 bp [1]
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • bitter taste receptor activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of bitter taste • detection of chemical stimulus involved in sensory perception of bitter taste • signal transduction • response to stimulus • sensory perception of taste • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	338398	387512
Ensembl	ENSG00000185899 ENSG00000285341	ENSMUSG00000056203
UniProt	P59551	Q7TQA9
RefSeq (mRNA)	NM_177437	NM_199159
RefSeq (protein)	NP_803186	NP_954610
Location (UCSC)	Chr 7: 143.44 – 143.44 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene. ^{[4] [5]}

See also

• Taste receptor

References

1. ENSG00000285341 GRCh38: Ensembl release 89: ENSG00000185899, ENSG00000285341 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID   12584440. S2CID   1542970.
5. "Entrez Gene: TAS2R60 taste receptor, type 2, member 60".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi: 10.1074/jbc.R100054200 . PMID   11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID   12139982. S2CID   37807140.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID   12581520. S2CID   718601.
• Shi P, Zhang J, Yang H, Zhang YP (2004). "Adaptive diversification of bitter taste receptor genes in Mammalian evolution". Mol. Biol. Evol. 20 (5): 805–14. doi: 10.1093/molbev/msg083 . PMID   12679530.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi: 10.1093/molbev/msi027 . PMID   15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC   1449719 . PMID   15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.