GPR148

GPR148
Identifiers
Aliases	GPR148 , BTR, PGR6, G protein-coupled receptor 148
External IDs	HomoloGene: 131347; GeneCards: GPR148; OMA:GPR148 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q21.1 Start 130,729,070 bp [1] End 130,730,336 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans cerebellum cerebellar hemisphere right hemisphere of cerebellum pituitary gland anterior pituitary primary visual cortex Brodmann area 9 hypothalamus rectum n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 344561 n/a Ensembl ENSG00000173302 n/a UniProt Q8TDV2 n/a RefSeq (mRNA) NM_207364 n/a RefSeq (protein) NP_997247 n/a Location (UCSC) Chr 2: 130.73 – 130.73 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

G protein-coupled receptor 148, also known as GPR148, is a human orphan receptor from GPCR superfamily. ^[3] It is expressed primarily in nervous system and testis. Is may be implicated in prostate cancer.

References

1. GRCh38: Ensembl release 89: ENSG00000173302 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: GPR148 G protein-coupled receptor 148".

Further reading

• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID   12044878. S2CID   7116392.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi: 10.1073/pnas.0230374100 . PMC   153653 . PMID   12679517.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Parmigiani RB, Magalhães GS, Galante PA, et al. (2005). "A novel human G protein-coupled receptor is over-expressed in prostate cancer". Genet. Mol. Res. 3 (4): 521–31. PMID   15688318.
• Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID   15777626.