GPR148

GPR148
Identifiers
Aliases	GPR148 , BTR, PGR6, G protein-coupled receptor 148
External IDs	HomoloGene: 131347 GeneCards: GPR148
Gene location (Human)
Chr.	Chromosome 2 (human)
End	130,730,336 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; cerebellum; ; cerebellar hemisphere; ; pituitary gland; ; anterior pituitary; ; Brodmann area 9; ; hypothalamus; ; rectum; ; prefrontal cortex; ; stomach;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity ; signal transducer activity ;
Cellular component	integral component of membrane ; plasma membrane ; membrane ;
Biological process	G protein-coupled receptor signaling pathway ; signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	344561
	n/a
	ENSG00000173302
	n/a
	Q8TDV2
	n/a
	NM_207364
	n/a
	NP_997247
	n/a
	Wikidata
View/Edit Human

Last updated August 19, 2023

G protein-coupled receptor 148, also known as GPR148, is a human orphan receptor from GPCR superfamily.^[3] It is expressed primarily in nervous system and testis. Is may be implicated in prostate cancer.

Related Research Articles

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Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene.

Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.

Probable G-protein coupled receptor 160 is a protein that in humans is encoded by the GPR160 gene.

Probable G-protein coupled receptor 82 is a protein that in humans is encoded by the GPR82 gene.

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.

Probable G-protein coupled receptor 87 is a protein that in humans is encoded by the GPR87 gene.

Probable G-protein coupled receptor 173 is a protein that in humans is encoded by the GPR173 gene.

Probable G-protein coupled receptor 135 is a protein that in humans is encoded by the GPR135 gene.

Probable G-protein coupled receptor 174 is a protein that in humans is encoded by the GPR174 gene.

Mas-related G-protein coupled receptor member E is a protein that in humans is encoded by the MRGPRE gene.

Integral membrane protein GPR155, also known as G protein-coupled receptor 155, is a protein that in humans is encoded by the GPR155 gene. Mutations in this gene may be associated with autism.

GPR113 is a gene that encodes the Probable G-protein coupled receptor 113 protein.

Probable G-protein coupled receptor 110 is a protein that in humans is encoded by the GPR110 gene. This gene encodes a member of the adhesion-GPCR receptor family. Family members are characterized by an extended extracellular region with a variable number of N-terminal protein modules coupled to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.

Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.

MAS-related GPR, member F, also known as MRGPRF, is a human gene.

Probable G-protein coupled receptor 176 is a protein that in humans is encoded by the GPR176 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000173302 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: GPR148 G protein-coupled receptor 148".

Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi: 10.1073/pnas.0230374100 . PMC 153653 . PMID 12679517.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Parmigiani RB, Magalhães GS, Galante PA, et al. (2005). "A novel human G protein-coupled receptor is over-expressed in prostate cancer". Genet. Mol. Res. 3 (4): 521–31. PMID 15688318.
Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000173302 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: GPR148 G protein-coupled receptor 148".

[1]

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[3]

GPR148

Related Research Articles

References

Further reading