GPR171

GPR171
Identifiers
Aliases	GPR171 , H963, G protein-coupled receptor 171
External IDs	MGI: 2442043 HomoloGene: 36330 GeneCards: GPR171
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q25.1 Start 151,197,832 bp [1] End 151,203,216 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 D Start 59,003,869 bp [2] End 59,009,242 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in appendix blood lymph node spleen superficial temporal artery amniotic fluid gallbladder rectum visceral pleura left uterine tube Top expressed in blood spleen thymus morula subcutaneous adipose tissue bone marrow blastocyst jejunum right lung lobe duodenum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled purinergic nucleotide receptor activity G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway negative regulation of myeloid cell differentiation signal transduction G protein-coupled purinergic nucleotide receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29909 229323 Ensembl ENSG00000174946 ENSMUSG00000050075 UniProt O14626 Q8BG55 RefSeq (mRNA) NM_013308 NM_173398 RefSeq (protein) NP_037440 NP_775574 Location (UCSC) Chr 3: 151.2 – 151.2 Mb Chr 3: 59 – 59.01 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 171 is a protein that in humans is encoded by the GPR171 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000174946 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050075 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jacobs KA, Collins-Racie LA, Colbert M, Duckett M, Golden-Fleet M, Kelleher K, Kriz R, LaVallie ER, Merberg D, Spaulding V, Stover J, Williamson MJ, McCoy JM (Dec 1997). "A genetic selection for isolating cDNAs encoding secreted proteins". Gene. 198 (1–2): 289–96. doi:10.1016/S0378-1119(97)00330-2. PMID   9370294.
6. "Entrez Gene: GPR171 G protein-coupled receptor 171".

Further reading

• Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID   7566098.
• Joensuu T, Hämäläinen R, Yuan B, et al. (2001). "Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3". Am. J. Hum. Genet. 69 (4): 673–84. doi:10.1086/323610. PMC   1226054 . PMID   11524702.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.