GPR37L1

GPR37L1
Identifiers
Aliases	GPR37L1 , ET(B)R-LP-2, ETBR-LP-2, G protein-coupled receptor 37 like 1, ETBRLP2
External IDs	OMIM: 617630 MGI: 1928503 HomoloGene: 3500 GeneCards: GPR37L1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q32.1 Start 202,122,886 bp [1] End 202,133,592 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 E4 Start 135,087,972 bp [2] End 135,095,419 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in caudate nucleus internal globus pallidus amygdala putamen nucleus accumbens endothelial cell cingulate gyrus Brodmann area 9 external globus pallidus hippocampus proper Top expressed in cerebellar vermis dorsal tegmental nucleus medulla oblongata superior colliculus globus pallidus medial vestibular nucleus inferior colliculus optic nerve ventral tegmental area pontine nuclei More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptide binding G protein-coupled peptide receptor activity protein binding G protein-coupled receptor activity signal transducer activity prosaposin receptor activity Cellular component integral component of membrane plasma membrane receptor complex membrane cell projection ciliary membrane Biological process positive regulation of cerebellar granule cell precursor proliferation negative regulation of astrocyte differentiation negative regulation of hydrogen peroxide-induced cell death adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway negative regulation of neuron differentiation negative regulation of smoothened signaling pathway positive regulation of MAPK cascade signal transduction G protein-coupled receptor signaling pathway negative regulation of systemic arterial blood pressure Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9283 171469 Ensembl ENSG00000170075 ENSMUSG00000026424 UniProt O60883 Q99JG2 RefSeq (mRNA) NM_004767 NM_134438 RefSeq (protein) NP_004758 NP_602320 Location (UCSC) Chr 1: 202.12 – 202.13 Mb Chr 1: 135.09 – 135.1 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Endothelin B receptor-like protein 2 is a protein that in humans is encoded by the GPR37L1 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000170075 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026424 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Valdenaire O, Giller T, Breu V, Ardati A, Schweizer A, Richards JG (Apr 1998). "A new family of orphan G protein-coupled receptors predominantly expressed in the brain". FEBS Lett. 424 (3): 193–6. doi: 10.1016/S0014-5793(98)00170-7 . PMID   9539149. S2CID   7999925.
6. "Entrez Gene: GPR37L1 G protein-coupled receptor 37 like 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.