Cycloproscaline

Last updated

Cycloproscaline
Cycloproscaline.svg
Clinical data
Other namesCP; 4-Cyclopropoxy-3,5-dimethoxyphenethylamine; 4-cPrO-3,5-DMPEA
Routes of
administration 		Oral [1] [2]
Drug class Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action ≥6 hours [1] [2]
Identifiers
  • 2-(4-cyclopropyloxy-3,5-dimethoxyphenyl)ethanamine
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C13H19NO3
Molar mass 237.299 g·mol−1
3D model (JSmol)
  • COC1=CC(=CC(=C1OC2CC2)OC)CCN
  • InChI=1S/C13H19NO3/c1-15-11-7-9(5-6-14)8-12(16-2)13(11)17-10-3-4-10/h7-8,10H,3-6,14H2,1-2H3
  • Key:VRTSLAVKWTZKIT-UHFFFAOYSA-N

Cycloproscaline (CP), also known as 4-cyclopropoxy-3,5-dimethoxyphenethylamine (4-cPrO-3,5-DMPEA), is a psychedelic drug of the phenethylamine and scaline families related to mescaline. [1] [2] It is the homologue of mescaline in which the 4-methoxy group has been replaced with a 4-cyclopropoxy group. [1] [2] The drug has a dose of 60 mg or more orally and a duration of 6 hours or more, but has not been fully evaluated. [1] [2] It is a low-potency full agonist of the serotonin 5-HT2A receptor and also interacts with other serotonin receptors such as the serotonin 5-HT1A and 5-HT2C receptors. [2] The drug's chemical synthesis has been described. [1] Cycloproscaline was first described in the scientific literature by Daniel Trachsel and colleagues in 2013. [1] Its pharmacology was studied in greater detail in 2021. [2]

Contents

See also

References

  1. 1 2 3 4 5 6 7 Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. pp. 706, 713–716. ISBN   978-3-03788-700-4. OCLC   858805226.
  2. 1 2 3 4 5 6 7 Kolaczynska KE, Luethi D, Trachsel D, Hoener MC, Liechti ME (2021). "Receptor Interaction Profiles of 4-Alkoxy-3,5-Dimethoxy-Phenethylamines (Mescaline Derivatives) and Related Amphetamines". Frontiers in Pharmacology. 12 794254. doi: 10.3389/fphar.2021.794254 . PMC   8865417 . PMID   35222010.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.