IRF9

Last updated
IRF9
Identifiers
Aliases IRF9 , IRF-9, ISGF3, ISGF3G, p48, interferon regulatory factor 9
External IDs OMIM: 147574; MGI: 107587; HomoloGene: 4436; GeneCards: IRF9; OMA:IRF9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006084
NM_001385400
NM_001385401
NM_001385402

NM_001159417
NM_001159418
NM_008394

RefSeq (protein)

NP_006075

NP_001152889
NP_001152890
NP_032420

Location (UCSC) Chr 14: 24.16 – 24.17 Mb Chr 14: 55.84 – 55.85 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. [5] [6] [7]

Contents

Interactions

IRF9 has been shown to interact with STAT2 [8] [9] and STAT1. [8]

References

  1. 1 2 3 ENSG00000285048 GRCh38: Ensembl release 89: ENSG00000213928, ENSG00000285048 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002325 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Veals SA, Schindler C, Leonard D, Fu XY, Aebersold R, Darnell JE Jr, Levy DE (Aug 1992). "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins". Mol Cell Biol. 12 (8): 3315–24. doi:10.1128/MCB.12.8.3315. PMC   364572 . PMID   1630447.
  6. McCusker D, Wilson M, Trowsdale J (Jun 1999). "Organization of the genes encoding the human proteasome activators PA28alpha and beta". Immunogenetics. 49 (5): 438–45. doi:10.1007/s002510050517. PMID   10199920. S2CID   40575791.
  7. "Entrez Gene: ISGF3G interferon-stimulated transcription factor 3, gamma 48kDa".
  8. 1 2 Horvath, C M; Stark G R; Kerr I M; Darnell J E (Dec 1996). "Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex". Mol. Cell. Biol. 16 (12). UNITED STATES: 6957–64. doi:10.1128/mcb.16.12.6957. ISSN   0270-7306. PMC   231699 . PMID   8943351.
  9. Martinez-Moczygemba, M; Gutch M J; French D L; Reich N C (Aug 1997). "Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3". J. Biol. Chem. 272 (32). UNITED STATES: 20070–6. doi: 10.1074/jbc.272.32.20070 . ISSN   0021-9258. PMID   9242679.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.