Forkhead box b1

FOXB1
Identifiers
Aliases	FOXB1 , FKH5, HFKH-5, forkhead box B1
External IDs	MGI: 1927549 HomoloGene: 8138 GeneCards: FOXB1
Gene location (Human)
Chr.	Chromosome 15 (human)
End	60,061,730 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	69,760,940 bp
Gene ontology
Molecular function	• DNA binding ; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity ; • GO:0001948 protein binding ; • sequence-specific DNA binding ; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	• nucleus ;
Biological process	• visual learning ; • somitogenesis ; • negative regulation of neuron apoptotic process ; • mammillary body development ; • mammillothalamic axonal tract development ; • regulation of transcription, DNA-templated ; • axon target recognition ; • mammary gland lobule development ; • thalamus development ; • transcription, DNA-templated ; • floor plate development ; • telencephalon cell migration ; • cell migration in diencephalon ; • inferior colliculus development ; • spinal cord development ; • urogenital system development ; • lactation ; • midbrain development ; • epithelial cell differentiation involved in mammary gland alveolus development ; • hypothalamus cell migration ; • regulation of transcription by RNA polymerase II ; • anatomical structure morphogenesis ; • cell differentiation ;
	Sources:Amigo / QuickGO
Orthologs
	27023
	64290
	ENSG00000171956
	ENSMUSG00000059246
	Q99853
	Q64732
	NM_012182
	NM_022378
	NP_036314
	NP_071773
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated June 07, 2021

Forkhead box B1 is a protein that in humans is encoded by the FOXB1 gene. ^[5]

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Forkead box I3 (FOXI3) is a protein that in humans is encoded by the FOXI3 gene. FOXI3 is a forkhead box transcription factor that is expressed in the development of hair and teeth. One of its mutations is a dominant allele responsible for the heterozygous Hh hairless trait in dogs. It was identified in 2008.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000171956 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059246 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Forkhead box B1" . Retrieved 2014-09-11.

Forkhead box b1

Related Research Articles

References

Further reading